Advanced Therapies NHS Readiness Toolkit

Poster outlining the approach to developing an NIHR Clinical Research Facility which is safe for the delivery of Oncology ATMP trials.

SOP to outline the framework and key aspects of training for pharmacists practicing within haematopoietic cellular therapies at The Christie NHS Trust.

Training package to prove nurses with knowledge, skills and expertise to perform specific apheresis procedures for cellular therapy in a safe and professional manner.

E-learning on the NHS e-learning platform e-learning for healthcare (registration required) giving the user an overview of the requirements for labelling human tissues and cells for use as starting materials for advanced therapy medicinal products using the ISBT 128 system.

PowerPoint presentation for an educational seminar on ATMP pharmacy.

Slides from a pharmacy teaching session on ATMPs from Manchester University NHS Foundation Trust

A presentation on ATMP Pharmacy Gene Therapy treatments.

E-learning on the NHS e-learning platform e-learning for healthcare (registration required) giving the user an overview of the procedural requirements for the procurement of human tissues and cells but does not discuss in depth the consent and ethics requirements

A training needs package and competency guide for healthcare and academic professionals involved in the delivery and direct care of patients receiving advanced therapy treatment; it provides information and signposting to external resources for independent training, learning and further reading on a number of key areas relevant to these medicines.

E-learning on the NHS e-learning platform e-learning for healthcare (registration required) giving the user a refresher of standard clinical trial studies and explains the additional features which impact on the design of trials for investigational advanced therapy medicinal products (ATIMPs) and how they can be addressed. Roles and responsibilities, governance and sources of support for ATIMP clinical trials are also outlined.

This document can be used to help prompt consideration and recording of the competencies that are needed to work safely while thawing.

This document can be used to help prompt consideration and recording of the competencies that are needed to work safely with dry shippers and/or dry ice.

A look at some of the recent impacts of ATMP treatments on children at the Royal Manchester Children’s Hospital

Focussing on four upcoming ATMPs in 2021, how they work, how patients might benefit, how they are given and other practical issues staff need to aware of.

A webinar giving an overview of governance, operational and clinical challenges which need to be overcome in order to implement these novel medicines

This training webinar gives an overview of basics of cell therapy and some applications

This training webinar gives an overview of the preparations required prior to treating patients with ATMPs

A webinar to give an introduction into the considerations for dosing patients with ATMPs

This is a training webinar that covers the basics and introduction of in vivo gene therapy

A training video demonstrating the thawing of a cryopreserved cell therapy product using a waterbath

Nitya, a university student from Gloucestershire, was the first patient to undergo CAR T cell therapy at the trust in February 2019. Hear from Nitya what it was like to receive CAR T cell therapy

A training resource on the importance of correctly thawing and inspecting cell therapy medicinal products

A training video explaining the logistics supply chain for ATMPs and autologous therapies in particular