The ATTC project aims to develop robust systems for the routine delivery of ATMPs as a standard of care throughout the NHS in the United Kingdom.
Over the last five years, new cell and gene therapies have been developed to treat some cancers and inherited diseases. These advanced therapies are different from existing treatments in two important ways: they are designed to restore normal function, sometimes offering cures where unmet medical need exists and they require new ways of working by the NHS.
The ATTC Network Programme is a world-first, UK system of Advanced Therapy Treatment Centres (ATTC) operating within the NHS framework and coordinated by the Cell and Gene Therapy Catapult that will address the unique and complex challenges of bringing pioneering advanced therapy medicinal products (ATMPs) to patients. The centres include:
- Innovate Manchester Advanced Therapy Centre Hub (iMATCH),
- Midlands-Wales Advanced Therapy Treatment Centre (MW-ATTC, comprising Birmingham, Wales and Nottingham) and
- Northern Alliance Advanced Therapies Treatment Centre (NAATTC, comprising Scotland, Newcastle and Leeds)
The network is initially supported by the Industrial Challenge Strategy Fund with the aim to develop first-of-a-kind technologies for the manufacture of innovative medicines across areas including blindness, cancer, heart failure, liver disease, neurological conditions and rare paediatric diseases.
As a goal of this three year project, the ATTCs will work together with industry partners and the public sector to develop the necessary processes, skilled staff and infrastructure at scale as more treatments move from clinical trial to marketed products.
The CGT Catapult will play a central coordination role for the network and provide support to manufacturing, supply chain logistics, regulatory affairs, clinical trial capability, R&D support and upskilling via specialist training and development.
CGT Catapult team
- Jacqueline Barry, Chief Clinical Officer
- Anna Outhwaite, Head of ATTC Network Coordination
- Tom Arnold, Network Programme Support Officer
- Paul Stroemer, Midlands and Wales Network Programme Manager
- Ian Hollingsworth, iMATCH Network Programme Manager
- Claire Brady, Northern Alliance Network Programme Manager