With an increased demand for ATMP administration services due to more ATMP treatments becoming standard of care and products demonstrating better safety data the NHS will need to increase capacity for ATMP administration. Patients are often required to receive ATMP treatments as an in-patient, commonly near to and with ease of access to high dependency units. Ambulatory Delivery of ATMPs can potentially offer hospitals an alternative.

University Hospitals Bristol and Weston NHS Foundation Trust have shared a suite of Standard Operation Procedures (SOPs) to assist NHS centres establishing the development of Ambulatory Delivery of ATMPs at their centre. The SOPs can be found here:

Ambulatory care for Lymphodepletion prior to CAR-T Cell Infusionhttps://theattc.wpengine.com/wp-content/uploads/2022/08/SpsAmbulatoryCareLymphodepletionPreCartInfusion-1_0.pdf

Assessment of Suitability for Ambulatory Care Bone Marrow Transplant (BMT) at Bristol Haematology and Oncology Centre (BHOC)https://theattc.wpengine.com/wp-content/uploads/2022/08/SpsAssessmentOfSuitabilityForAmbulatoryCareBmtAtBh-1_0.pdf

High-dose Melphalan with Stem Cell Rescue (Autologous Stem Cell Transplant, ASCT) in the Outpatient Setting https://theattc.wpengine.com/wp-content/uploads/2022/08/SpsHighDoseMelphalanWithStemCellRescueautologousSt-1_1.pdf

Shared Care for Adult CAR-T Patientshttps://theattc.wpengine.com/wp-content/uploads/2022/08/SpsSharedCareForCartPatients-2.pdf