A suite of local SOPs and guidance documents to support the delivery of CAR-T cell therapy have been provided by the Newcastle upon Tyne Hospitals NHS Foundation Trust’s Haematology department. These documents are available via the ATTC Knowledge Hub and will be a valuable resource for clinical sites preparing to deliver CAR-T cell therapy and align their local procedures and documentation with JACIE standards.
The suite of documents includes:
- CAR-T Cell Therapy Consent Form for Relapsed Remitting ALL
- CAR-T Consent Form for DLBCL
- CAR-T Discharge Letter
- CAR-T Training Slides for Nurses
- Cytokine Release Syndrome (CRS) Assessment for CAR-T
- Infusions of CAR-T Cells SOP
- Management of CRA, Neurotoxicity and CAR-T Cell Related Encephalopathy Syndrome (CRES) Post CAR-T
- Neurotoxicity Assessment for CAR-T cell Therapy
- Conditioning Protocol for DLBCL for CAR-T (Tisagenlecleucel (Kymriah®)(Novartis)
