A severe side effect of CAR T-cell therapy in which the immune response can produce a toxic effect on the nervous system. Patients may suffer headaches, confusion, seizures, loss of speech and loss of motor skills. ICANS can range from very mild to quite severe and life-threatening.
Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS, or neurotoxicity)
attcadmn2021-08-28T21:56:18+01:0028th August 2021|