The CAR T-Cell Therapy Clinical Journey Guide

Glossary

Gene Therapy

A therapy that uses genes to treat or prevent disease. In CAR T-cell therapy, a gene carrying instructions to make a new protein receptor is inserted into T cells.

Gene Therapy Advisory Committee (GTAC)

The UK national REC for gene therapy clinical research.

Genes

Stretches of DNA that serve as the “instructions” or blueprints for cells to make proteins.